CSVApr 10, 2026· 5 min

GAMP 5: categorizing GxP software to scope validation

GAMP 5 provides a risk-based approach to validating computer systems in GxP environments.

Main categories

Software is categorized by degree of customization — from infrastructure and commercial off-the-shelf (COTS) products to configured and bespoke systems. The more customization, the larger the validation effort.

Practical meaning

Categorization drives the required document set (DQ/IQ/OQ/PQ) and the depth of testing. A risk-based mindset focuses resources where risk is highest.

Written by

Nguyễn Hải Đăng

Operations Digital Transformation Advisor · 7 years digitalizing factory operations

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